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Activation of the AMPK-Sirtuins-PGC1 pathway promotes mitochondrial biogenesis and function while regulating fission, fusion, and mitophagy processes, ultimately reserving organelle quality [86]

75 There is a mitochondrial targeting sequence (MTS) attached to the N-terminus of PINK1, allowing PINK1 to be introduced into the IMM through translocases located in both of the OMM and the IMM in a mitochondrial transmembrane potential-dependent way

[Google Scholar] Pathogenesis, epidemiology and control of Group A Streptococcus infection

Its chelating properties allow it to inhibit proteolytic activity and prevent excess calcium ions [81], protecting against opacification induced by calcium content dysregulation